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Using HPC Techniques to Accelerate NGS Workflows

Life Sciences_small

Next-generation sequencing (NGS) describes the modern nucleotide sequencing technologies that allow analysis of genetic material with unprecedented speed and efficiency. Its advent is shifting genome assembly from a problem of laboratory-based chemistry to one well suited to high performance computing (HPC). In simple terms, NGS involves breaking up long DNA or RNA molecules into millions of small, fragments (50 to 200 nucleotides), defined as a “reads” to be assembled into larger fragments called contigs. The process of taking genetic material, processing it on a sequencer, passing it to an HPC system for assembly, and outputting digital information in a form useful for research is contained in a “workflow,” the end-to-end flow … [Read more...]

Video Blog: Solutions that Enable Life Sciences Advances

Ted Slater

Advanced IT solutions are transforming the life sciences industry, and there are few better places to learn about how this is happening than the Bio-IT World Conference & Expo in Boston. The conference is coming up soon, and at Cray, we're excited to highlight our computing, storage and analysis solutions. Ted Slater, senior solutions architect for life sciences at YarcData, a Cray company, will present on Wednesday, April 30, and talk about how YarcData’s Urika technology is fueling major advances. Ted's presentation, "Learn How YarcData's Graph Analytics Appliance Makes It Easy to Use Big Data in Life Sciences," is about how data-intensive research is rising in life sciences and how YarcData systems provide the functionality … [Read more...]

University of Chicago Researchers Make Strides in Genome Sequencing

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When Charles Darwin explored the Galapagos Islands and developed his theory of natural selection, he did so with the help of the H.M.S. Beagle.  The University of Chicago is building on his pioneering work using a supercomputer and storage provided by Cray, also called the Beagle. Darwin's ship gained historic status not because it was particularly unique or special, but because it was the vehicle that carried him to the locations where he completed research that redefined the way we look at evolutionary theory. The Beagle became famous because it was a tool that enabled Darwin to do his work. Theories are essential, but tools are the means by which researchers test their hypotheses and make new discoveries. Today, high performance … [Read more...]

Cray Supercomputers Powering Scientific Research in Chemistry and Life Sciences

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In recent months, several chemistry and life sciences organizations have turned to Cray supercomputers to power their scientific research. Among them we welcome Duke University, the National Institute of Environmental Health Sciences, Université Laval in Canada, S.N. Bose in India, and the PDC Center for High-Performance Computing at the KTH Royal Institute of Technology in Sweden, as well as a number of leading pharmaceutical companies and biotechs. These organizations are doing groundbreaking work, and providing them with Cray supercomputers is representative of our growing presence in this vitally important segment. Chemistry and life sciences researchers are certainly no strangers to HPC. In fact, as part of the 2013 HPCwire … [Read more...]

Another Exciting Year

Pete's Blog_holiday 2013

As we near the end of 2013, Cray is closing out one of the most transformative years in our long and proud history. In just this year alone, we successfully integrated two strategic acquisitions, won a number of large supercomputing contracts at customer sites around the world, significantly expanded our business and portfolio of solutions, continued to build the financial strength of the company, and added a host of highly-talented individuals to our team. It’s been quite a year! Since the early days of our company, starting with our iconic founder Seymour Cray, we have been a trusted partner to customers around the world with a commitment to do two things really well:  be focused on their success and help them to see around the next … [Read more...]